Penfil is a medication prescribed to treat erectile dysfunction (ED). The drug increases blood flow to the penis during sexual stimulation.
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Tadalafil, commonly sold under the brand name Penfil Tablet, serves various purposes in the realm of men's health:
Avoid consuming alcohol while taking Tadalafil as it can intensify dizziness.
Penfil 10mg Tablet is considered unsafe for use during pregnancy. It's advisable not to use this medication if you are pregnant or planning to become pregnant. Consult your healthcare provider for alternative options.
Similar to pregnancy, Penfil 10mg Tablet is not recommended for breastfeeding mothers. It's safer to explore other treatment options while nursing your baby.
Tadalafil may cause dizziness, so exercise caution when operating vehicles or machinery. Ensure that you are fully alert before engaging in activities that require focus and attention.
Kidney impairment or kidney disease may also require dosage adjustments. Prior to taking Penfil 10mg Tablet, consult your healthcare provider and discuss any concerns you have about your kidney function.
If you have liver impairment or liver disease, it may be necessary to adjust the dosage of Penfil 10mg Tablet. Consult your doctor before using this medication, and inform them of any concerns or conditions related to your liver health.
In some cases, yes, though this is usually to treat medical conditions other than ED. A person can take the medication daily or when needed, but they should first discuss dosage and frequency with their doctor.
Common side effects may include headache, myalgia, respiratory tract infection, nasal pharyngitis, dyspepsia, flushing, back pain, and nausea. Less common side effects can involve changes in color vision, sudden vision loss, hearing loss, skin reactions like Stevens-Johnson Syndrome, angina, stroke, myocardial infarction, severe hypotension, and tachycardia.
Erectile dysfunction (impotence), benign prostatic hyperplasia (BPH), Pulmonary arterial hypertension (PAH)
Tadalafil is a PDE5 (phosphodiesterase type 5) inhibitor. By inhibiting PDE5, it increases cGMP levels in smooth muscle cells. Elevated cGMP levels relax smooth muscles and enhance blood flow to the corpus cavernosum, facilitating penile erection. PDE5 is also present in the smooth muscles of the prostate and bladder wall. Inhibiting PDE5 raises cGMP concentrations, resulting in smooth muscle relaxation in the prostate and bladder. This relaxation may improve blood flow to the urinary system and enlarge the bladder neck opening, facilitating more efficient voiding.
Erectile Dysfunction: Typically, the recommended starting dose is 10 mg, with the option to increase to 20 mg or decrease to 5 mg based on individual needs. The maximum frequency of use is once daily, and the effect can last up to 36 hours.
Benign Prostatic Hyperplasia: The recommended dose is 5 mg taken at the same time daily.
Combined Erectile Dysfunction and Benign Prostatic Hyperplasia: The recommended dose is 5 mg daily.
Tadalafil may interact with medications such as nitrates, alpha-adrenergic blockers, antihypertensives, alcohol, certain antacids, ketoconazole, ritonavir, erythromycin, itraconazole, grapefruit juice, other HIV protease inhibitors, rifampin, carbamazepine, phenytoin, and phenobarbital.
Tadalafil is classified as pregnancy category B by the USFDA. Its use during pregnancy should only occur if the benefits outweigh the risks. There is limited information on Tadalafil excretion in human milk, so caution is necessary when administering it to breastfeeding women.
Caution is advised in patients with anatomical penile deformations, cardiovascular disease, history of myocardial infarction or stroke within the last 90 days, unstable angina, heart failure, uncontrolled arrhythmias, hypotension, uncontrolled hypertension, recent cerebrovascular accident, bleeding disorders, active peptic ulcer disease, liver disease, renal impairment, conditions predisposing to priapism, and concomitant use of CYP3A4 inhibitors.
Store in a cool, dry place away from light and heat. Keep out of the reach of children.
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